A small peptide encoded within mitochondrial DNA (a 'mitochondrial-derived peptide') that has been studied for cytoprotective and metabolic signaling in aging research.
Mechanism under study
Humanin is associated with anti-apoptotic and cytoprotective signaling through receptor complexes, and has been linked in preclinical work to improved insulin sensitivity and neuroprotection.
Research-reported dosing
No established human dosing; research is preclinical, largely using potent analogs such as HNG.
Dosing figures describe how this compound appears in the research literature and research-community references. They are not a recommendation for human use.
Humanin FAQ
What is Humanin?
A small peptide encoded within mitochondrial DNA (a 'mitochondrial-derived peptide') that has been studied for cytoprotective and metabolic signaling in aging research.
What is the half-life of Humanin?
Short; native humanin is rapidly cleared, and more stable analogs (such as the S14G 'HNG' variant) are commonly used in research.
What is the research-reported dosing for Humanin?
No established human dosing; research is preclinical, largely using potent analogs such as HNG.
How is Humanin reconstituted?
5 mg vial + 2 mL bacteriostatic water = 2500 mcg/mL.
Is Humanin FDA-approved?
No — Humanin is not FDA-approved and is sold for laboratory research use only.
References
Guides featuring Humanin
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