A coenzyme central to cellular energy metabolism and DNA-repair signaling. Levels decline with age, making it a major focus of longevity and mitochondrial research. Included here as a commonly co-studied research cofactor.
Mechanism under study
Serves as an essential electron carrier in redox reactions and a substrate for sirtuins and PARPs — enzymes tied to DNA repair, metabolic regulation, and cellular stress responses.
Research-reported dosing
Research references span a wide range (e.g., ~100–500 mg subcutaneous references, plus IV protocols). Oral precursors are studied separately. Not an established therapeutic here.
Based on a standard 500 mg vial: with 3 mL bacteriostatic water = 166,667 mcg/mL (166.7 mg/mL); 1 unit ≈ 1.7 mg.
A 50 mg dose ≈ 30 units (1666.67 mcg per unit).
Open this mix in the calculator →Source research-grade NAD+ ↗Dosing figures describe how this compound appears in the research literature and research-community references. They are not a recommendation for human use.
NAD+ FAQ
What is NAD+?
A coenzyme central to cellular energy metabolism and DNA-repair signaling. Levels decline with age, making it a major focus of longevity and mitochondrial research. Included here as a commonly co-studied research cofactor.
What is the half-life of NAD+?
Rapidly metabolized; precursors (NMN, NR) are frequently studied for oral bioavailability.
What is the research-reported dosing for NAD+?
Research references span a wide range (e.g., ~100–500 mg subcutaneous references, plus IV protocols). Oral precursors are studied separately. Not an established therapeutic here.
How is NAD+ reconstituted?
Based on a standard 500 mg vial: with 3 mL bacteriostatic water = 166,667 mcg/mL (166.7 mg/mL); 1 unit ≈ 1.7 mg.
Is NAD+ FDA-approved?
No — NAD+ is not FDA-approved and is sold for laboratory research use only.
References
Guides featuring NAD+
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