A mitochondrial-derived peptide studied as a metabolic regulator and exercise-mimetic in preclinical models, and of interest in aging and insulin-sensitivity research.
Mechanism under study
Studied for activating the AMPK energy-sensing pathway, influencing glucose metabolism, and translocating to the nucleus to regulate stress-response genes.
Research-reported dosing
Preclinical and research-community references vary widely (commonly cited in ~5–10 mg weekly ranges, split). Not established in humans.
Based on a standard 10 mg vial: with 2 mL bacteriostatic water = 5,000 mcg/mL (5 mg/mL); 1 unit ≈ 50 mcg.
A 5 mg dose ≈ 100 units (50 mcg per unit).
Open this mix in the calculator →Source research-grade MOTS-c ↗Dosing figures describe how this compound appears in the research literature and research-community references. They are not a recommendation for human use.
MOTS-c FAQ
What is MOTS-c?
A mitochondrial-derived peptide studied as a metabolic regulator and exercise-mimetic in preclinical models, and of interest in aging and insulin-sensitivity research.
What is the half-life of MOTS-c?
Short systemically; research references intermittent dosing schedules.
What is the research-reported dosing for MOTS-c?
Preclinical and research-community references vary widely (commonly cited in ~5–10 mg weekly ranges, split). Not established in humans.
How is MOTS-c reconstituted?
Based on a standard 10 mg vial: with 2 mL bacteriostatic water = 5,000 mcg/mL (5 mg/mL); 1 unit ≈ 50 mcg.
Is MOTS-c FDA-approved?
No — MOTS-c is not FDA-approved and is sold for laboratory research use only.
References
Guides featuring MOTS-c
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