A small-molecule inhibitor of the enzyme NNMT — not a peptide — studied mainly in cell and animal models for its effects on fat-cell metabolism and its potential to preserve NAD+.
Mechanism under study
By inhibiting nicotinamide N-methyltransferase (NNMT), it is proposed to shift metabolism in adipocytes and spare NAD+ and related methylation substrates, associations drawn largely from preclinical work.
Research-reported dosing
No established human clinical dosing; effects on fat metabolism are from cell and animal studies. Research-community sources reference oral doses in the tens-of-milligrams range, without clinical validation.
Typically supplied as oral capsules rather than a lyophilized vial; as an illustration only, 50 mg of powder + 2 mL solvent = 25000 mcg/mL (25 mg/mL).
Open this mix in the calculator →Dosing figures describe how this compound appears in the research literature and research-community references. They are not a recommendation for human use.
5-Amino-1MQ FAQ
What is 5-Amino-1MQ?
A small-molecule inhibitor of the enzyme NNMT — not a peptide — studied mainly in cell and animal models for its effects on fat-cell metabolism and its potential to preserve NAD+.
What is the half-life of 5-Amino-1MQ?
Not well characterized in humans; as a small molecule its behavior differs from peptides, and evidence is largely from cell and animal studies.
What is the research-reported dosing for 5-Amino-1MQ?
No established human clinical dosing; effects on fat metabolism are from cell and animal studies. Research-community sources reference oral doses in the tens-of-milligrams range, without clinical validation.
How is 5-Amino-1MQ reconstituted?
Typically supplied as oral capsules rather than a lyophilized vial; as an illustration only, 50 mg of powder + 2 mL solvent = 25000 mcg/mL (25 mg/mL).
Is 5-Amino-1MQ FDA-approved?
No — 5-Amino-1MQ is not FDA-approved and is sold for laboratory research use only.
References
Related peptides
NAD+
Cellular coenzyme (not a peptide; included as a research cofactor)
A coenzyme central to cellular energy metabolism and DNA-repair signaling. Levels decline with age, making it a major focus of longevity and mitochondrial research. Included here as a commonly co-studied research cofactor.
MOTS-c
Mitochondrial-derived peptide
A mitochondrial-derived peptide studied as a metabolic regulator and exercise-mimetic in preclinical models, and of interest in aging and insulin-sensitivity research.
Epithalon
Synthetic tetrapeptide
A synthetic tetrapeptide derived from the pineal peptide epithalamin, studied in longevity research — notably for reported effects on telomerase activity in cell and animal models.