Thymulin is a nine-amino-acid thymic peptide hormone that requires bound zinc for biological activity. Secreted by thymic epithelial cells, it participates in T-cell differentiation and immune regulation and has been studied for immunomodulation, inflammation, and (in analog form) pain and neuroinflammation. It is investigational.
Mechanism under study
Only the zinc-bound form is biologically active; thymulin promotes T-lymphocyte maturation and modulates cytokine release, with reported anti-inflammatory and neuroendocrine-interacting effects. Its activity is tightly coupled to zinc status, so zinc deficiency lowers active thymulin.
Research-reported dosing
No established standardized human dosing; experimental and animal studies use microgram-level amounts, and zinc co-availability is emphasized as essential for activity. Investigational/research-only; not an approved drug.
5 mg vial + 2 mL bacteriostatic water = 2,500 mcg/mL (2.5 mg/mL); 1 unit is approximately 0.025 mg (25 mcg). Because activity is zinc-dependent, zinc status is a research consideration alongside preparation.
Open this mix in the calculator →Dosing figures describe how this compound appears in the research literature and research-community references. They are not a recommendation for human use.
Thymulin FAQ
What is Thymulin?
Thymulin is a nine-amino-acid thymic peptide hormone that requires bound zinc for biological activity. Secreted by thymic epithelial cells, it participates in T-cell differentiation and immune regulation and has been studied for immunomodulation, inflammation, and (in analog form) pain and neuroinflammation. It is investigational.
What is the half-life of Thymulin?
Short in circulation (reported on the order of minutes); measurable activity depends on adequate zinc availability.
What is the research-reported dosing for Thymulin?
No established standardized human dosing; experimental and animal studies use microgram-level amounts, and zinc co-availability is emphasized as essential for activity. Investigational/research-only; not an approved drug.
How is Thymulin reconstituted?
5 mg vial + 2 mL bacteriostatic water = 2,500 mcg/mL (2.5 mg/mL); 1 unit is approximately 0.025 mg (25 mcg). Because activity is zinc-dependent, zinc status is a research consideration alongside preparation.
Is Thymulin FDA-approved?
Thymulin has an approved status in at least one context — see the overview above for the specific brand, region, and indication. Research-grade material sold separately is for laboratory use only.
References
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