The only human cathelicidin antimicrobial peptide, studied for direct antimicrobial activity as well as roles in inflammation and wound healing. Human therapeutic use is investigational.
Mechanism under study
LL-37 disrupts microbial membranes and neutralizes bacterial LPS, while also acting as an immune modulator — recruiting immune cells and influencing angiogenesis and wound repair in preclinical studies.
Research-reported dosing
No established human dosing; work is largely preclinical, spanning antimicrobial, wound-healing, and immunomodulatory models.
Dosing figures describe how this compound appears in the research literature and research-community references. They are not a recommendation for human use.
LL-37 FAQ
What is LL-37?
The only human cathelicidin antimicrobial peptide, studied for direct antimicrobial activity as well as roles in inflammation and wound healing. Human therapeutic use is investigational.
What is the half-life of LL-37?
Short; rapidly degraded by proteases in most reported settings.
What is the research-reported dosing for LL-37?
No established human dosing; work is largely preclinical, spanning antimicrobial, wound-healing, and immunomodulatory models.
How is LL-37 reconstituted?
5 mg vial + 2 mL bacteriostatic water = 2500 mcg/mL.
Is LL-37 FDA-approved?
No — LL-37 is investigational and not FDA-approved. It is sold for laboratory research use only.
References
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