A tripeptide fragment (Lys-Pro-Val) derived from the C-terminus of alpha-MSH, studied for anti-inflammatory effects, particularly in models of gut inflammation.
Mechanism under study
KPV is proposed to enter cells and dampen pro-inflammatory signaling — notably NF-kB activity and downstream cytokines — without the pigmentation effects of the full alpha-MSH molecule.
Research-reported dosing
No established human dosing; anti-inflammatory effects are reported mainly in cell and rodent gut-inflammation models. Research-community sources reference oral and subcutaneous use.
Based on a standard 10 mg vial: with 2 mL bacteriostatic water = 5,000 mcg/mL (5 mg/mL); 1 unit ≈ 50 mcg.
Open this mix in the calculator →Source research-grade KPV ↗Dosing figures describe how this compound appears in the research literature and research-community references. They are not a recommendation for human use.
KPV FAQ
What is KPV?
A tripeptide fragment (Lys-Pro-Val) derived from the C-terminus of alpha-MSH, studied for anti-inflammatory effects, particularly in models of gut inflammation.
What is the half-life of KPV?
Short, as expected for a tripeptide.
What is the research-reported dosing for KPV?
No established human dosing; anti-inflammatory effects are reported mainly in cell and rodent gut-inflammation models. Research-community sources reference oral and subcutaneous use.
How is KPV reconstituted?
Based on a standard 10 mg vial: with 2 mL bacteriostatic water = 5,000 mcg/mL (5 mg/mL); 1 unit ≈ 50 mcg.
Is KPV FDA-approved?
No — KPV is not FDA-approved and is sold for laboratory research use only.
References
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