For laboratory research use only — not for human or veterinary consumption.
The Peptide Index
PI-037

PEG-MGF

Pegylated IGF-1 splice variant (Mechano Growth Factor)

A pegylated form of Mechano Growth Factor, a splice variant of IGF-1 linked to muscle repair. Human data are limited and its use is investigational.

Mechanism under study

MGF (an IGF-1 splice variant expressed after mechanical loading or damage) is proposed to activate muscle satellite (stem) cells to support local repair and growth; PEGylation is intended to slow clearance and prolong exposure.

Research-reported dosing

No established human dosing; use is investigational/preclinical. Research-community sources reference roughly 200-400 mcg per dose.

Reconstitution

5 mg vial + 2 mL bacteriostatic water = 2500 mcg/mL.

A 300 mcg dose ≈ 12 units (25 mcg per unit).

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Dosing figures describe how this compound appears in the research literature and research-community references. They are not a recommendation for human use.

PEG-MGF FAQ

What is PEG-MGF?

A pegylated form of Mechano Growth Factor, a splice variant of IGF-1 linked to muscle repair. Human data are limited and its use is investigational.

What is the half-life of PEG-MGF?

Native MGF is cleared within minutes; PEGylation is intended to extend this to hours or longer, though human data are lacking.

What is the research-reported dosing for PEG-MGF?

No established human dosing; use is investigational/preclinical. Research-community sources reference roughly 200-400 mcg per dose.

How is PEG-MGF reconstituted?

5 mg vial + 2 mL bacteriostatic water = 2500 mcg/mL.

Is PEG-MGF FDA-approved?

No — PEG-MGF is investigational and not FDA-approved. It is sold for laboratory research use only.

References

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