Thymalin is a peptide fraction extracted from thymus tissue and used in Russian clinical research as an immunomodulator intended to restore T-cell balance in aging and illness. It is used as a drug in Russia but is not FDA-approved, and most evidence comes from Russian-language literature.
Mechanism under study
A thymus-derived peptide fraction proposed to normalize T-lymphocyte subsets and cytokine balance, supporting cell-mediated immunity, particularly in aging or immunosuppressed states.
Research-reported dosing
Not FDA-approved, though used as a drug in Russia. Russian clinical reports describe roughly 10 mg intramuscularly once daily for 5-10 day courses; no validated Western dosing exists. Reported, not recommended.
A peptide fraction supplied as lyophilized powder and historically given intramuscularly. A 10 mg vial reconstituted with 2 mL bacteriostatic water yields 5,000 mcg/mL (5 mg/mL); on a U-100 syringe 1 unit (0.01 mL) is about 50 mcg. Research use only in the West.
Open this mix in the calculator →Dosing figures describe how this compound appears in the research literature and research-community references. They are not a recommendation for human use.
Thymalin FAQ
What is Thymalin?
Thymalin is a peptide fraction extracted from thymus tissue and used in Russian clinical research as an immunomodulator intended to restore T-cell balance in aging and illness. It is used as a drug in Russia but is not FDA-approved, and most evidence comes from Russian-language literature.
What is the half-life of Thymalin?
Not well characterized; as a mixed peptide fraction it is expected to clear rapidly.
What is the research-reported dosing for Thymalin?
Not FDA-approved, though used as a drug in Russia. Russian clinical reports describe roughly 10 mg intramuscularly once daily for 5-10 day courses; no validated Western dosing exists. Reported, not recommended.
How is Thymalin reconstituted?
A peptide fraction supplied as lyophilized powder and historically given intramuscularly. A 10 mg vial reconstituted with 2 mL bacteriostatic water yields 5,000 mcg/mL (5 mg/mL); on a U-100 syringe 1 unit (0.01 mL) is about 50 mcg. Research use only in the West.
Is Thymalin FDA-approved?
Thymalin has an approved status in at least one context — see the overview above for the specific brand, region, and indication. Research-grade material sold separately is for laboratory use only.
References
Related peptides
Thymosin Alpha-1
Immunomodulatory 28-amino-acid peptide
An immune-modulating 28-amino-acid peptide, marketed as Zadaxin in a number of countries. It is among the more clinically studied immune peptides, though it is not FDA-approved in the United States.
Thymulin
Zinc-dependent nonapeptide thymic hormone
Thymulin is a nine-amino-acid thymic peptide hormone that requires bound zinc for biological activity. Secreted by thymic epithelial cells, it participates in T-cell differentiation and immune regulation and has been studied for immunomodulation, inflammation, and (in analog form) pain and neuroinflammation. It is investigational.
Thymosin Beta-4
43-amino-acid actin-sequestering peptide (full-length thymosin beta-4)
Thymosin beta-4 is a naturally occurring 43-amino-acid peptide and a major intracellular actin-sequestering molecule. It is the full-length parent from which the research fragment commonly sold as TB-500 is derived, and it is studied for tissue repair, angiogenesis, and cell migration. It remains investigational.
Epithalon
Synthetic tetrapeptide
A synthetic tetrapeptide derived from the pineal peptide epithalamin, studied in longevity research — notably for reported effects on telomerase activity in cell and animal models.