For laboratory research use only — not for human or veterinary consumption.
The Peptide Index
PI-002

TB-500

Synthetic actin-binding peptide fragment

A synthetic fragment related to Thymosin Beta-4, a naturally occurring actin-regulating peptide. Studied in preclinical models for cell migration, wound healing, and flexibility.

Mechanism under study

Thymosin Beta-4 sequesters G-actin and promotes cell migration and blood-vessel formation; the TB-500 fragment is studied for similar pro-migratory and reparative effects in injured tissue.

Research-reported dosing

Research-community references commonly cite ~2–2.5 mg once or twice weekly during an initial period, tapering thereafter. Not established in humans.

Reconstitution

Based on a standard 10 mg vial: with 2 mL bacteriostatic water = 5,000 mcg/mL (5 mg/mL); 1 unit ≈ 50 mcg.

A 2 mg dose ≈ 40 units (50 mcg per unit).

Open this mix in the calculator →Source research-grade TB-500 ↗

Dosing figures describe how this compound appears in the research literature and research-community references. They are not a recommendation for human use.

TB-500 comparisons

TB-500 FAQ

What is TB-500?

A synthetic fragment related to Thymosin Beta-4, a naturally occurring actin-regulating peptide. Studied in preclinical models for cell migration, wound healing, and flexibility.

What is the half-life of TB-500?

Reported longer-acting than many peptides; research references dosing 1–2× weekly.

What is the research-reported dosing for TB-500?

Research-community references commonly cite ~2–2.5 mg once or twice weekly during an initial period, tapering thereafter. Not established in humans.

How is TB-500 reconstituted?

Based on a standard 10 mg vial: with 2 mL bacteriostatic water = 5,000 mcg/mL (5 mg/mL); 1 unit ≈ 50 mcg.

Is TB-500 FDA-approved?

No — TB-500 is not FDA-approved and is sold for laboratory research use only.

References

Guides featuring TB-500

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