TB-500 Dosage Chart & Schedule
A synthetic fragment related to Thymosin Beta-4, a naturally occurring actin-regulating peptide. Studied in preclinical models for cell migration, wound healing, and flexibility.
Reported protocols commonly cite a loading phase of ~2-2.5 mg twice weekly (about 4-5 mg/week) for 4-6 weeks, then taper to a weekly maintenance dose. Longer-acting than most peptides and not established in humans.
Figures describe how TB-500 is reported in the research literature and research-community references — not a recommendation for human use. For laboratory research only.
Dosage protocols
Commonly referenced research tiers. Start conservative; every compound and study context differs.
- Frequency
- 2x/week
- Weekly total
- 4-5 mg
- Cycle
- First 4-6 weeks
The most commonly referenced starting pattern: a weekly total split into two subQ doses during an initial block.
- Frequency
- Once weekly
- Weekly total
- 2-2.5 mg
- Cycle
- After loading, tapering
A lower weekly reference used after the loading period given the compound's longer duration of action.
Longer-acting than most peptides
- TB-500 is referenced with once- or twice-weekly dosing rather than daily, reflecting a longer duration of action than short-half-life peptides.
- A loading-then-maintenance pattern is the common research convention, not a clinically validated schedule.
Fragment vs full Thymosin Beta-4
- TB-500 is commonly supplied as a synthetic fragment or analog related to Thymosin Beta-4 rather than the full-length protein; exact sequence varies by source.
- Not established in humans; evidence is preclinical.
Ready to run this protocol?
Dosing is only as good as the vial. TB-500 is third-party tested with published COAs from our top-rated source — reconstitute with confidence and skip the guesswork on identity and purity.
Weekly schedule
A typical week on the loading protocol (2x/week).
Dosing day Off
TB-500 reconstitution
Based on a standard 10 mg vial: with 2 mL bacteriostatic water = 5,000 mcg/mL (5 mg/mL); 1 unit ≈ 50 mcg.
From vial to injection in 6 steps
Wipe both vial tops
Swab the peptide vial and the bacteriostatic-water vial with fresh alcohol and let them dry.
Draw the water
Pull the planned amount of bacteriostatic water (2 mL) into the syringe.
Add it slowly
Run the water down the inside wall of the vial — don't blast the powder. Swirl gently; never shake.
Let it dissolve
Wait until the solution is fully clear, then refrigerate the vial.
Draw your dose
Pull the calculated units on a U-100 insulin syringe (~40 units for 2 mg).
Store between uses
Keep the reconstituted vial refrigerated and use within its stable window.
Handling & storage
- Reconstitute with bacteriostatic water (2 mL into a 10 mg vial = 5000 mcg/mL)
- Refrigerate reconstituted; keep the lyophilized powder cool and dark
- A 2 mg dose draws to ~40 units on a U-100 insulin syringe
TB-500 dosing FAQ
How much TB-500 per week?
Research references commonly cite ~4-5 mg/week during an initial loading period (e.g., 2-2.5 mg twice weekly), tapering to a lower weekly maintenance dose. Not established in humans.
How is TB-500 reconstituted?
With bacteriostatic water. For example, 2 mL into a 10 mg vial = 5000 mcg/mL, so a 2 mg dose is about 40 units on a U-100 syringe.
Why is TB-500 dosed only once or twice a week?
It is referenced as longer-acting than many peptides, so protocols use less-frequent dosing than daily compounds.
Is TB-500 combined with BPC-157?
The two are frequently referenced together in recovery-research discussions, but combined dosing is a convention rather than a proven protocol.
Sources
Categories: Healing & Recovery · Status: Research use only. This page is educational and for laboratory research use only; it is not medical advice.