For laboratory research use only — not for human or veterinary consumption.
The Peptide Index
PI-019

Melanotan II

Melanocortin receptor agonist

A synthetic melanocortin agonist studied for skin pigmentation (tanning) and, secondarily, arousal. It is not approved, and research notes meaningful safety considerations.

Mechanism under study

Non-selectively activates melanocortin receptors, stimulating melanogenesis (via MC1R) and influencing appetite and arousal (via MC4R).

Research-reported dosing

Research-community references cite small amounts (~0.25–1 mg) during an initial period. It is unapproved; moles/pigmentation changes and nausea are noted research safety considerations.

Reconstitution

Based on a standard 10 mg vial: with 2 mL bacteriostatic water = 5,000 mcg/mL (5 mg/mL); 1 unit ≈ 50 mcg.

A 500 mcg dose ≈ 10 units (50 mcg per unit).

Open this mix in the calculator →Source research-grade Melanotan II ↗

Dosing figures describe how this compound appears in the research literature and research-community references. They are not a recommendation for human use.

Melanotan II FAQ

What is Melanotan II?

A synthetic melanocortin agonist studied for skin pigmentation (tanning) and, secondarily, arousal. It is not approved, and research notes meaningful safety considerations.

What is the half-life of Melanotan II?

Reported around 30–60 minutes.

What is the research-reported dosing for Melanotan II?

Research-community references cite small amounts (~0.25–1 mg) during an initial period. It is unapproved; moles/pigmentation changes and nausea are noted research safety considerations.

How is Melanotan II reconstituted?

Based on a standard 10 mg vial: with 2 mL bacteriostatic water = 5,000 mcg/mL (5 mg/mL); 1 unit ≈ 50 mcg.

Is Melanotan II FDA-approved?

No — Melanotan II is not FDA-approved and is sold for laboratory research use only.

References

Guides featuring Melanotan II

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