A synthetic form of gonadotropin-releasing hormone (GnRH). It has established diagnostic and fertility uses and is also used off-label to support endogenous hormone production.
Mechanism under study
Given in a pulsatile pattern, gonadorelin stimulates the pituitary to release LH and FSH; continuous rather than pulsatile exposure instead downregulates these signals.
Research-reported dosing
Has regulatory-approved diagnostic use (about 100 mcg IV/SC) and pulsatile-pump fertility use (roughly 5-20 mcg per pulse). Also used off-label in the TRT community to support endogenous testicular function.
2 mg vial + 2 mL bacteriostatic water = 1000 mcg/mL.
A 100 mcg dose ≈ 10 units (10 mcg per unit).
Open this mix in the calculator →Dosing figures describe how this compound appears in the research literature and research-community references. They are not a recommendation for human use.
Gonadorelin FAQ
What is Gonadorelin?
A synthetic form of gonadotropin-releasing hormone (GnRH). It has established diagnostic and fertility uses and is also used off-label to support endogenous hormone production.
What is the half-life of Gonadorelin?
Very short — reported roughly 2-10 minutes, which is why pulsatile delivery is used clinically.
What is the research-reported dosing for Gonadorelin?
Has regulatory-approved diagnostic use (about 100 mcg IV/SC) and pulsatile-pump fertility use (roughly 5-20 mcg per pulse). Also used off-label in the TRT community to support endogenous testicular function.
How is Gonadorelin reconstituted?
2 mg vial + 2 mL bacteriostatic water = 1000 mcg/mL.
Is Gonadorelin FDA-approved?
No — Gonadorelin is not FDA-approved and is sold for laboratory research use only.
References
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