For laboratory research use only — not for human or veterinary consumption.
The Peptide Index
Dosing guide

IGF-1 LR3 Dosage Chart & Schedule

A modified, long-acting analog of insulin-like growth factor 1 widely used as a research reagent in cell-culture and preclinical growth studies.

Route
Subcutaneous
Frequency
Once daily
Half-life
Extended versus native IGF
Storage
Refrigerate reconstituted; keep lyophilized vial cool and dark
The short answer

As a potent, long-acting research reagent, references vary widely but commonly fall in a ~20-50 mcg once-daily range in animal and lab work. It is not established or appropriate as a human therapeutic.

Figures describe how IGF-1 LR3 is reported in the research literature and research-community references — not a recommendation for human use. For laboratory research only.

Dosage protocols

Commonly referenced research tiers. Start conservative; every compound and study context differs.

Starter
20 mcg
per injection
Frequency
Once daily
Weekly total
~0.14 mg
Cycle
Short blocks (research reference)

A low end of the referenced research-reagent range; IGF-1 LR3 is potent, so amounts stay in the low microgram range.

Most commonStandard
40 mcg
per injection
Frequency
Once daily
Weekly total
~0.28 mg
Cycle
Short blocks (research reference)

A commonly referenced mid-range research amount; the extended half-life supports once-daily timing.

A research reagent, not a therapeutic

  • IGF-1 LR3 is widely used as a cell-culture and preclinical reagent; its dosing references come from animal and lab work.
  • It is not established or appropriate as a human therapeutic.

Potent and long-acting

  • The Long R3 modifications reduce binding to IGF-binding proteins, extending activity to ~20-30 hours and increasing potency.
  • Because of this potency, research amounts sit in the tens-of-micrograms range, far below most peptides.

Ready to run this protocol?

Dosing is only as good as the vial. IGF-1 LR3 is third-party tested with published COAs from our top-rated source — reconstitute with confidence and skip the guesswork on identity and purity.

Weekly schedule

A typical week on the standard protocol (Once daily).

Mon
Tue
Wed
Thu
Fri
Sat
Sun

Dosing day Off

IGF-1 LR3 reconstitution

Based on a standard 1 mg vial: with 2 mL bacteriostatic water = 500 mcg/mL (0.5 mg/mL); 1 unit ≈ 5 mcg.

Concentration
500 mcg/mL
Per syringe unit
5 mcg
Draw for 40 mcg
8 units
Doses per vial
~25
Open this mix in the calculator →

From vial to injection in 6 steps

1

Wipe both vial tops

Swab the peptide vial and the bacteriostatic-water vial with fresh alcohol and let them dry.

2

Draw the water

Pull the planned amount of bacteriostatic water (2 mL) into the syringe.

3

Add it slowly

Run the water down the inside wall of the vial — don't blast the powder. Swirl gently; never shake.

4

Let it dissolve

Wait until the solution is fully clear, then refrigerate the vial.

5

Draw your dose

Pull the calculated units on a U-100 insulin syringe (~8 units for 40 mcg).

6

Store between uses

Keep the reconstituted vial refrigerated and use within its stable window.

Handling & storage

  • Reconstitute with bacteriostatic water (2 mL into a 1 mg vial = 500 mcg/mL); some lab protocols use dilute acetic acid or 0.1% BSA for longer stability
  • Refrigerate reconstituted; keep the lyophilized powder cool and dark
  • A 40 mcg dose draws to ~8 units on a U-100 insulin syringe (20 mcg = ~4 units)

IGF-1 LR3 dosing FAQ

How much IGF-1 LR3 per day?

As a research reagent, references vary widely and commonly fall in a ~20-50 mcg range in animal work, roughly 0.14-0.35 mg/week. It is not established or appropriate as a human therapeutic.

How is IGF-1 LR3 reconstituted?

With bacteriostatic water. For example, 2 mL into a 1 mg vial = 500 mcg/mL, so a 40 mcg dose is about 8 units on a U-100 syringe; some lab protocols use an acidified diluent for longer stability.

Why is IGF-1 LR3 dosed in such small amounts?

The Long R3 modifications make it potent and long-acting (~20-30 h half-life), so research amounts are in the tens-of-micrograms range, far lower than most peptides.

How often is IGF-1 LR3 administered in research?

Its extended half-life supports once-daily references in short blocks. As a lab reagent this is not a human-use recommendation.

Sources

Categories: Healing & Recovery · Status: Research use only. This page is educational and for laboratory research use only; it is not medical advice.