For laboratory research use only — not for human or veterinary consumption.
The Peptide Index
PI-066

Noopept

Dipeptide-derived nootropic (small molecule, oral)

Noopept is a synthetic dipeptide-derived nootropic (N-phenylacetyl-L-prolylglycine ethyl ester) developed in Russia and taken orally, not by injection. It is a prescription nootropic in Russia and sold elsewhere as a supplement, but it is not FDA-approved and robust independent clinical evidence is limited.

Mechanism under study

Proposed to modulate AMPA and NMDA glutamate signaling and to raise BDNF and NGF expression, with antioxidant and neuroprotective actions; one metabolite resembles the endogenous neuropeptide cycloprolylglycine.

Research-reported dosing

Not FDA-approved; a prescription nootropic in Russia and a supplement in some other markets. Studies and label use report roughly 10 mg orally two to three times daily (about 20-30 mg/day); it is oral, not injected. Reported, not recommended.

Reconstitution

Not a water-reconstituted injectable. Noopept is taken orally as a tablet, capsule, or sublingual powder; bacteriostatic water reconstitution does not apply.

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Dosing figures describe how this compound appears in the research literature and research-community references. They are not a recommendation for human use.

Noopept FAQ

What is Noopept?

Noopept is a synthetic dipeptide-derived nootropic (N-phenylacetyl-L-prolylglycine ethyl ester) developed in Russia and taken orally, not by injection. It is a prescription nootropic in Russia and sold elsewhere as a supplement, but it is not FDA-approved and robust independent clinical evidence is limited.

What is the half-life of Noopept?

Very short plasma half-life for the parent compound, reported on the order of minutes, with activity attributed largely to active metabolites.

What is the research-reported dosing for Noopept?

Not FDA-approved; a prescription nootropic in Russia and a supplement in some other markets. Studies and label use report roughly 10 mg orally two to three times daily (about 20-30 mg/day); it is oral, not injected. Reported, not recommended.

How is Noopept reconstituted?

Not a water-reconstituted injectable. Noopept is taken orally as a tablet, capsule, or sublingual powder; bacteriostatic water reconstitution does not apply.

Is Noopept FDA-approved?

Noopept has an approved status in at least one context — see the overview above for the specific brand, region, and indication. Research-grade material sold separately is for laboratory use only.

References

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