For laboratory research use only — not for human or veterinary consumption.
The Peptide Index
Dosing guide

MGF (Mechano Growth Factor) Dosage Chart & Schedule

MGF (Mechano Growth Factor) is a splice variant of IGF-1 known as IGF-1Ec, expressed transiently by muscle after mechanical loading or damage. The non-pegylated form described here is very short-acting and is distinct from the stabilized PEG-MGF variant. Evidence is preclinical and it is not an approved therapeutic.

Route
Subcutaneous
Frequency
Post-workout (research)
Half-life
Very short, reported as only a few minutes, which is the rationale for the pegylated PEG
Storage
Lyophilized: cool or frozen. Reconstituted: refrigerate 2-8 C.
The short answer

MGF is a very short-acting, non-pegylated IGF-1 splice variant (IGF-1Ec) studied only in preclinical muscle-repair models, with no approved human use. Non-clinical sources reference small localized post-exercise amounts (roughly 100-200 mcg), but no validated human dosing exists, and this form is distinct from the longer-acting PEG-MGF variant.

Figures describe how MGF (Mechano Growth Factor) is reported in the research literature and research-community references — not a recommendation for human use. For laboratory research only.

Dosage protocols

Commonly referenced research tiers. Start conservative; every compound and study context differs.

Starter
100 mcg
About 10 units at 1 mg/mL (2 mg + 2 mL)
Frequency
Post-workout on training days (non-clinical reference)
Weekly total
About 300-400 mcg/week (training days)
Cycle
No established cycle; short non-clinical references only

Low end of the range cited on non-clinical forums.

Most commonStandard
200 mcg
About 20 units at 1 mg/mL (2 mg + 2 mL)
Frequency
Post-workout near the trained muscle (non-clinical reference)
Weekly total
About 600-800 mcg/week (training days)
Cycle
No established cycle; short non-clinical references only

Upper end of forum figures (about 100-200 mcg); not a validated dose.

Very short half-life

  • Non-pegylated MGF is reported to last only minutes in circulation.
  • That short window is the rationale for the stabilized PEG-MGF variant.
  • Non-clinical sources reference dosing close to training as a result.

Preclinical only

  • MGF is studied in preclinical muscle-repair models, not approved for human use.
  • Dose figures around 100-200 mcg are forum references, not validated protocols.

Ready to run this protocol?

Dosing is only as good as the vial. Research-grade peptides are third-party tested with published COAs from our top-rated source — reconstitute with confidence and skip the guesswork on identity and purity.

MGF (Mechano Growth Factor) reconstitution

Research lyophilate. A 2 mg vial reconstituted with 2 mL bacteriostatic water yields 1,000 mcg/mL (1 mg/mL); on a U-100 syringe 1 unit (0.01 mL) is about 10 mcg. Research use only.

Concentration
1,000 mcg/mL
Per syringe unit
10 mcg
Draw for 200 mcg
20 units
Doses per vial
~10
Open this mix in the calculator →

From vial to injection in 6 steps

1

Wipe both vial tops

Swab the peptide vial and the bacteriostatic-water vial with fresh alcohol and let them dry.

2

Draw the water

Pull the planned amount of bacteriostatic water (2 mL) into the syringe.

3

Add it slowly

Run the water down the inside wall of the vial — don't blast the powder. Swirl gently; never shake.

4

Let it dissolve

Wait until the solution is fully clear, then refrigerate the vial.

5

Draw your dose

Pull the calculated units on a U-100 insulin syringe (~20 units for 200 mcg).

6

Store between uses

Keep the reconstituted vial refrigerated and use within its stable window.

Handling & storage

  • A 2 mg vial with 2 mL bacteriostatic water gives 1 mg/mL (1,000 mcg/mL); one U-100 unit is about 10 mcg.
  • Reconstitute gently and refrigerate; use promptly given its fragility.
  • This is the non-PEG form; PEG-MGF is a different, longer-acting variant with different references.
  • Research use only.

MGF (Mechano Growth Factor) dosing FAQ

What is a commonly referenced MGF amount?

Non-clinical sources reference roughly 100-200 mcg near the trained muscle after exercise. This is reported context from a preclinical compound, not a recommendation.

How is non-PEG MGF different from PEG-MGF for dosing?

Non-PEG MGF lasts only minutes, so it is referenced around training, whereas PEG-MGF is pegylated to last longer and is dosed less frequently.

How much is one unit on the syringe?

At a 2 mg + 2 mL mix (1 mg/mL), one U-100 unit (0.01 mL) is about 10 mcg, so 200 mcg is roughly 20 units.

Is there human dosing data?

No. MGF has been studied in preclinical models only, with no approved human use and no validated human dosing.

Sources

Full MGF (Mechano Growth Factor) reference →All dosing charts →

Categories: Growth Hormone Secretagogues, Healing & Recovery · Status: Research use only. This page is educational and for laboratory research use only; it is not medical advice.