IGF-1 DES (1-3) Dosage Chart & Schedule
IGF-1 DES(1-3) is a truncated form of insulin-like growth factor 1 missing its first three N-terminal amino acids, a change that sharply lowers binding to IGF-binding proteins and increases potency. It is a laboratory research reagent with no approved human use and essentially no controlled human data.
IGF-1 DES(1-3) is a truncated, more potent IGF-1 analog used only as a laboratory and animal research reagent, with no approved human use and essentially no controlled human data. Non-clinical sources reference small localized amounts (roughly 20-50 mcg), but no validated human dosing exists.
Figures describe how IGF-1 DES (1-3) is reported in the research literature and research-community references — not a recommendation for human use. For laboratory research only.
Dosage protocols
Commonly referenced research tiers. Start conservative; every compound and study context differs.
- Frequency
- Post-workout on training days (non-clinical reference)
- Weekly total
- About 60-80 mcg/week (training days)
- Cycle
- No established cycle; short non-clinical references only
Low end of the range cited on non-clinical forums.
- Frequency
- Post-workout on training days (non-clinical reference)
- Weekly total
- About 120-160 mcg/week (training days)
- Cycle
- No established cycle; short non-clinical references only
Mid-range of forum figures (about 20-50 mcg); not a validated dose.
No human dosing exists
- IGF-1 DES(1-3) has no approved human use and essentially no controlled human data.
- Dose figures around 20-50 mcg come from non-clinical forums, not validated protocols.
- Removing the first three N-terminal residues lowers IGF-binding-protein capture, making it more potent than native IGF-1.
Ready to run this protocol?
Dosing is only as good as the vial. Research-grade peptides are third-party tested with published COAs from our top-rated source — reconstitute with confidence and skip the guesswork on identity and purity.
IGF-1 DES (1-3) reconstitution
Research lyophilate. A 1 mg vial reconstituted with 2 mL bacteriostatic water yields 500 mcg/mL; on a U-100 syringe 1 unit (0.01 mL) is about 5 mcg. Research use only.
From vial to injection in 6 steps
Wipe both vial tops
Swab the peptide vial and the bacteriostatic-water vial with fresh alcohol and let them dry.
Draw the water
Pull the planned amount of bacteriostatic water (2 mL) into the syringe.
Add it slowly
Run the water down the inside wall of the vial — don't blast the powder. Swirl gently; never shake.
Let it dissolve
Wait until the solution is fully clear, then refrigerate the vial.
Draw your dose
Pull the calculated units on a U-100 insulin syringe (~8 units for 40 mcg).
Store between uses
Keep the reconstituted vial refrigerated and use within its stable window.
Handling & storage
- A 1 mg vial with 2 mL bacteriostatic water gives 500 mcg/mL; one U-100 unit is about 5 mcg.
- Reconstitute gently and refrigerate; IGF peptides are fragile in solution.
- Because free IGF-1 clears within minutes, non-clinical use references timing around training.
- Research use only; high potency means small volume changes shift the amount substantially.
IGF-1 DES (1-3) dosing FAQ
Is there an established human dose for IGF-1 DES?
No. It is a laboratory and animal research reagent with no approved human use; figures around 20-50 mcg come from non-clinical forums, not validated protocols.
How much is in one syringe unit?
At the common 1 mg + 2 mL mix (500 mcg/mL), one U-100 unit (0.01 mL) is about 5 mcg, so a 40 mcg reference amount is roughly 8 units.
How does it differ from IGF-1 LR3 on dosing?
Both evade IGF-binding proteins, but DES(1-3) is very short-acting while LR3 is long-acting; non-clinical references dose DES around training rather than once daily.
Why is timing described as post-workout?
Because free IGF-1 clears within minutes, non-clinical sources reference administration close to training near the worked area. This is reported context, not a recommendation.
Sources
Categories: Healing & Recovery · Status: Research use only. This page is educational and for laboratory research use only; it is not medical advice.