For laboratory research use only — not for human or veterinary consumption.
The Peptide Index
Dosing guide

Dihexa Dosage Chart & Schedule

Dihexa is a small angiotensin IV-derived peptide analog developed as a candidate for cognitive disorders. In preclinical work it is reported to potentiate hepatocyte growth factor (HGF) signaling at the c-Met receptor and to promote synaptogenesis. Human data are essentially absent; it is preclinical/research-only.

Route
Oral
Frequency
No validated human dose
Half-life
Not well characterized in humans
Storage
Keep dry, cool, and away from light; if dissolved in solvent, refrigerate.
The short answer

Dihexa has essentially no human dosing data. It is a very potent, highly lipophilic angiotensin IV analog studied mainly in rodents; research-community anecdotes cite low-milligram oral amounts, but these are unvalidated.

Figures describe how Dihexa is reported in the research literature and research-community references — not a recommendation for human use. For laboratory research only.

Dosage protocols

Commonly referenced research tiers. Start conservative; every compound and study context differs.

Most commonResearch anecdote only
Low single-digit mg (anecdotal)
Oral; no controlled human data supports any specific amount.
Frequency
Anecdotally once daily
Weekly total
Not established
Cycle
Not established

Dihexa is reported to be extremely potent in preclinical assays, so anecdotal amounts are small and entirely unvalidated in humans.

Preclinical potency, no human pharmacokinetics

  • In rodent work dihexa is reported to potentiate HGF/c-Met signaling and promote synaptogenesis at very low doses.
  • Human half-life and safe dosing are unpublished; all human-use amounts circulating in communities are extrapolations, not trial data.

Ready to run this protocol?

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Weekly schedule

A typical week on the research anecdote only protocol (Anecdotally once daily).

Mon
Tue
Wed
Thu
Fri
Sat
Sun

Dosing day Off

Handling & storage

  • Dihexa is highly lipophilic and is typically dissolved in a solvent vehicle such as DMSO or an oil carrier, not bacteriostatic water.
  • It is not a standard water-reconstituted U-100 injectable; handling follows its solubility.
  • Preclinical/research-only compound with no established human safety data.

Dihexa dosing FAQ

Is there a standard dihexa dose?

No. There is no established or validated human dose. Rodent studies use microgram-to-low-milligram-per-kilogram amounts, and community anecdotes cite low single-digit milligrams orally, but none of this is supported by human trials.

Why is dihexa dosed so low?

It is reported to be very potent in preclinical models, so referenced amounts are small. Potency does not equal safety, and the human dose-response is simply unknown.

How is dihexa prepared?

Because it is highly lipophilic, it is handled dissolved in a solvent such as DMSO or an oil, rather than mixed with bacteriostatic water like a typical injectable peptide.

Is dihexa taken orally or injected?

Preclinical studies have used both oral and injected routes; research-community use is usually described as oral, but no route has a validated human protocol.

Sources

Categories: Nootropic & Cognitive · Status: Research use only. This page is educational and for laboratory research use only; it is not medical advice.